1-Iodopropane → HCID 67317167, compound

HRID 1014184Notes

Reaction equation

HRID 1014184 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[N:11][CH:12]=[CH:13][CH:14]=2)=[CH:5][C:4]=1[N+:15]([O-:17])=[O:16].[CH2:18]([I:21])[CH2:19][CH3:20]>CC(=O)C(C)(C)C>[I-:21].[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([C:9]2[CH:10]=[N+:11]([CH2:18][CH2:19][CH3:20])[CH:12]=[CH:13][CH:14]=2)=[CH:5][C:4]=1[N+:15]([O-:17])=[O:16]

Participants

4

Reactant 2

HCID 336431-IodopropaneHCID 13734413HCID 13734413, compound

Product 1

HCID 67317167HCID 67317167, compound

Reagents, catalysts & solvents 1

HCID 6416PinacoloneSolvent

Conditions

Temperature
95 °C

Procedure

To pinacolone (50 mL, Aldrich) was added 3-[4-(methyloxy)-3-nitrophenyl]pyridine (3.5 g, 15.22 mmol) and propyliodide (10.46 g, 61.52 mmol, Fluke). The reaction was stirred at 95° C. overnight. The solvent was decanted and the remaining solids were dried under reduced pressure overnight to provide 3-[4-(methyloxy)-3-nitrophenyl]-1-propylpyridinium iodide, which was use for the next reaction without further purification.

Workup

  1. customThe solvent was decanted
  2. customthe remaining solids were dried under reduced pressure overnight

Sources & evidence

ORD record
ord-a3f936ad0f0649988da74d72065e14f0
Source dataset
uspto-grants-2011_07
Patent number
US07981903B2

Reaction notes

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