HCID 69958659, compound → HCID 18407017, compound

HRID 1016444Notes

Reaction equation

HRID 1016444 reaction equation
C([N:8]1[CH2:13][CH2:12][C:11](=[CH:14][C:15]2[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=2)[CH:10]([CH3:21])[CH2:9]1)C1C=CC=CC=1.[H][H]>C(O)C.[OH-].[OH-].[Pd+2]>[CH2:14]([CH:11]1[CH2:12][CH2:13][NH:8][CH2:9][CH:10]1[CH3:21])[C:15]1[CH:20]=[CH:19][CH:18]=[CH:17][CH:16]=1

Participants

5

Reactant 2

HCID 69958659HCID 69958659, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18407017HCID 18407017, compoundYield 108.6%

Reagents, catalysts & solvents 2

HCID 9942167Palladium hydroxideCatalystHCID 702EthanolSolvent

Procedure

A solution of 2.7 g of 1-benzyl-4-benzylidene-3-methyl-piperidine and 2 g of 20% palladium hydroxide on carbon in 125 mL of ethanol was shaken 3 days under 55 psi of hydrogen. The catalyst was filtered off and the solution concentrated to give 2 g of a mixture of cis and trans-4-benzyl-3-methyl-piperidine as an oil.

Workup

  1. filtrationThe catalyst was filtered off
  2. concentrationthe solution concentrated

Sources & evidence

ORD record
ord-1536bdac76ac4efd8505b344a76dcc25
Source dataset
uspto-grants-2002_11
Patent number
US06476041B1

Reaction notes

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