4-Chloro-1-butanol → 1-(4-Hydroxybutyl)-4-piperidone

HRID 1017370Notes

Reaction equation

[NH:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1.Cl[CH2:9][CH2:10][CH2:11][CH2:12][OH:13]>>[OH:13][CH2:12][CH2:11][CH2:10][CH2:9][N:1]1[CH2:6][CH2:5][C:4](=[O:7])[CH2:3][CH2:2]1

Participants

Reactant 2

HCID 135694-Chloro-1-butanol

HCID 337214-Piperidone

Product 1

HCID 180017351-(4-Hydroxybutyl)-4-piperidone

Procedure

1-(4-Hydroxybutyl)-4-piperidone is prepared from 4-piperidone and 4-chloro-1-butanol essentially as described above in Example 38, Scheme C, step a.

Sources & evidence

ORD record: ord-8e94eb96860a4d1aab4012fcdd150dac
Source dataset: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US06479487B1

Reaction notes

Loading…