Methanol → HCID 18404976, compound

HRID 1017784Notes

Reaction equation

HRID 1017784 reaction equation
[N+:1]([C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11]1[CH:16]=[CH:15][C:14]([Br:17])=[CH:13][C:12]=1[CH3:18])([O-])=O.CO.[H][H]>[Pt].ClCCl>[NH2:1][C:4]1[CH:9]=[CH:8][CH:7]=[CH:6][C:5]=1[NH:10][C:11]1[CH:16]=[CH:15][C:14]([Br:17])=[CH:13][C:12]=1[CH3:18]

Participants

6

Reactant 3

HCID 887MethanolHCID 18404979HCID 18404979, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 18404976HCID 18404976, compound

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 6344DichloromethaneSolvent

Procedure

A suspension of 5.34 g (17.4 mmol) of N-(2-nitrophenyl)-4-bromo-2-methyl-aniline and 1.7 g of platinum on charcoal is stirred in 100 ml of dichloromethane and 100 ml of methanol at a hydrogen pressure of 3 bar for 1 hour. Then the catalyst is filtered off and the filtrate is evaporated down.

Workup

  1. filtrationThen the catalyst is filtered off
  2. customthe filtrate is evaporated down

Sources & evidence

ORD record
ord-0fbd836485324b7d8e7545ea167022f6
Source dataset
uspto-grants-2002_11
Patent number
US06479524B1

Reaction notes

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