HRID1018569

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID7294

Methyl acrylate

C4H6O2

反应SMILES：O=C(c1cc(C(F)(F)F)cc(C(F)(F)F)c1)N1CCC2(CC1)C(=O)NCN2c1ccccc1

HCID18401725

未命名化合物

PRODUCTS

产物

反应SMILES：COC(=O)CCN1CN(c2ccccc2)C2(CCN(C(=O)c3cc(C(F)(F)F)cc(C(F)(F)F)c3)CC2)C1=O

HCID86584184

未命名化合物

PROCEDURE

实验过程

The title compound, MS: m/e=558.2 (M+H+), was prepared in accordance with the general method of example 59 from 8-(3,5-bis-trifluoromethyl-benzoyl)-1-phenyl-1,3,8-triaza-spiro[4.5]decan-4-one and methyl acrylate.

来源与证据

来源类型: Open Reaction Database
ORD记录: ord-d087d74983c54e8d926f539ee456e14e
来源数据集: uspto-grants-2002_11
DOI: 10.6084/m9.figshare.5104873.v1
专利号: US06482829B2
来源说明: uspto-grants-2002_11

反应SMILES

[F:1][C:2]([F:33])([F:32])[C:3]1[CH:4]=[C:5]([CH:25]=[C:26]([C:28]([F:31])([F:30])[F:29])[CH:27]=1)[C:6]([N:8]1[CH2:24][CH2:23][C:11]2([N:15]([C:16]3[CH:21]=[CH:20][CH:19]=[CH:18][CH:17]=3)[CH2:14][NH:13][C:12]2=[O:22])[CH2:10][CH2:9]1)=[O:7].[C:34]([O:38][CH3:39])(=[O:37])[CH:35]=[CH2:36]>>[CH3:39][O:38][C:34](=[O:37])[CH2:35][CH2:36][N:13]1[C:12](=[O:22])[C:11]2([CH2:10][CH2:9][N:8]([C:6](=[O:7])[C:5]3[CH:25]=[C:26]([C:28]([F:31])([F:30])[F:29])[CH:27]=[C:3]([C:2]([F:1])([F:32])[F:33])[CH:4]=3)[CH2:24][CH2:23]2)[N:15]([C:16]2[CH:17]=[CH:18][CH:19]=[CH:20][CH:21]=2)[CH2:14]1