Acetonitrile → 4-(4-Isopropyl-phenylcarbamoyl)-piperidine-1-carboxylic acid tert-butyl ester
Reaction equation
[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:15])[OH:16])[CH2:12][CH2:13]1.[CH3:28][N:29]1[CH2:30][CH2:31][O:32][CH2:33][CH2:34]1.[CH3:45][C:46]#[N:47].[CH:35]([CH3:36])([CH3:37])[c:38]1[cH:39][cH:40][c:41]([NH2:44])[cH:42][cH:43]1.[Cl:17][c:18]1[n:19][c:20]([O:21][CH3:22])[n:23][c:24]([O:25][CH3:26])[n:27]1>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH2:10][CH:11]([C:14](=[O:16])[NH:44][c:41]2[cH:40][cH:39][c:38]([CH:35]([CH3:36])[CH3:37])[cH:43][cH:42]2)[CH2:12][CH2:13]1Participants
6
Sources & evidence
- ORD record
- ord-0510f4e9eb1c4a7cb109805fac1352b3
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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