Dichloromethane → N-(2-chloropyridin-4-yl)-6-((trans)-4-(2-cyanoacetamido)cyclohexylamino)-8-(cyclopropylamino)imidazo[1,2-b]pyridazine-3-carboxamide
Reaction equation
[C:41](#[N:42])[CH2:43][C:44](=[O:45])[OH:46].[CH:32]([N:33]([CH2:34][CH3:35])[CH:36]([CH3:37])[CH3:38])([CH3:39])[CH3:40].[Cl:47][CH2:48][Cl:49].[NH2:1][CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[cH:10][c:11]([NH:28][CH:29]3[CH2:30][CH2:31]3)[c:12]3[n:13]([n:14]2)[c:15]([C:18](=[O:19])[NH:20][c:21]2[cH:22][c:23]([Cl:27])[n:24][cH:25][cH:26]2)[cH:16][n:17]3)[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][CH:5]([NH:8][c:9]2[cH:10][c:11]([NH:28][CH:29]3[CH2:30][CH2:31]3)[c:12]3[n:13]([n:14]2)[c:15]([C:18](=[O:19])[NH:20][c:21]2[cH:22][c:23]([Cl:27])[n:24][cH:25][cH:26]2)[cH:16][n:17]3)[CH2:6][CH2:7]1)[C:44]([CH2:43][C:41]#[N:42])=[O:45]Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-48ff2cf54ce644c280a06f80bfc6fe38
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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