Methyl chloroacetate → HCID 85706506, compound

HRID 1022657Notes

Reaction equation

HRID 1022657 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]([CH:7]=[CH:8][C:9]=1[Cl:10])[CH:5]=[O:6].Cl[CH2:12][C:13]([O:15][CH3:16])=[O:14].C[O-].[Na+].CO>CO>[Cl:1][C:2]1[CH:3]=[C:4]([CH:5]2[O:6][CH:12]2[C:13]([O:15][CH3:16])=[O:14])[CH:7]=[CH:8][C:9]=1[Cl:10]

Participants

5

Reactant 3

HCID 7295Methyl chloroacetateHCID 227103,4-DichlorobenzaldehydeHCID 23694274Sodium methanolate methanol

Product 1

HCID 85706506HCID 85706506, compound

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

To a solution of 3,4-dichlorobenzaldehyde (51.0 g) and methyl chloroacetate (51 mL) in methanol (500 mL) was added 28% sodium methoxide/methanol (68 mL) solution under ice-cooling, and the mixture was stirred at room temperature overnight. The resultant product was collected by filtration, and washed with distilled water to give the title compound (90.9 g).

Workup

  1. temperaturecooling
  2. filtrationThe resultant product was collected by filtration
  3. washwashed with distilled water

Sources & evidence

ORD record
ord-320308a3e3694e529aef9ab12a06f3f3
Source dataset
uspto-grants-2014_05
Patent number
US08722662B2

Reaction notes

Loading…