Diethylamine → HCID 66818676, compound

HRID 1024725Notes

Reaction equation

HRID 1024725 reaction equation
[C:1]([C:3]1[CH:27]=[CH:26][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[C:15]([O:17][C:18]3[CH:23]=[CH:22][C:21]([C:24]#[N:25])=[CH:20][CH:19]=3)[CH:16]=2)[C:11]([OH:13])=O)=[CH:5][CH:4]=1)#[N:2].[CH2:28]([NH:30][CH2:31][CH3:32])[CH3:29]>>[C:1]([C:3]1[CH:4]=[CH:5][C:6]([O:7][C:8]2[CH:9]=[C:10]([CH:14]=[C:15]([O:17][C:18]3[CH:19]=[CH:20][C:21]([C:24]#[N:25])=[CH:22][CH:23]=3)[CH:16]=2)[C:11]([N:30]([CH2:31][CH3:32])[CH2:28][CH3:29])=[O:13])=[CH:26][CH:27]=1)#[N:2]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 66818818HCID 66818818, compound

Product 1

HCID 66818676HCID 66818676, compoundYield 72.3%

Procedure

Following the procedure of Example 5(c) 3,5-bis-(4-cyano-phenoxy)-benzoic acid 1.2 g (3.36 mmol) and diethyl-amine (0.245 g, 3.36 mmol) were used to afford 1.0 g of the required product. 1H NMR (DMSO-d6): δ 1.15 (6H, m), 3.22 (2H, m), 3.40 (2H, m), 6.94 (2H, d), 7.05 (1H, t), 7.25 (2H, d), 7.88 (2H, d).

Sources & evidence

ORD record
ord-4abe7342802d478c94f8e80dd43da264
Source dataset
uspto-grants-2014_05
Patent number
US08722930B2

Reaction notes

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