反应详情

To the product from step A (7.79 mmol, 1.84 g) in THF (15 mL) was added HCl (45 mmol, 15 mL). The reaction was stirred overnight and subsequently quenched using Na2CO3. The reaction was then extracted using EtOAc (3×100 mL). The organic layers were combined, dried and concentrated in vacuo to afford the desired ketone (780 mg, 52%). MS [M+H]+ 193.1.

1. customsubsequently quenched
2. extractionThe reaction was then extracted
3. customdried
4. concentrationconcentrated in vacuo