Methane → Methyl 4-amino-5-methylthiophene-2-carboxylate

HRID 102586Notes

Reaction equation

HRID 102586 reaction equation
[C:19].[CH3:1][c:2]1[c:3]([N+:11]([O-:12])=[O:13])[cH:4][c:5]([C:7](=[O:8])[O:9][CH3:10])[s:6]1.[O:14]1[CH2:15][CH2:16][CH2:17][CH2:18]1.[Pd:20]>>[CH3:1][c:2]1[c:3]([NH2:11])[cH:4][c:5]([C:7](=[O:8])[O:9][CH3:10])[s:6]1

Participants

5

Reactant 4

HCID 297MethaneHCID 8028TetrahydrofuranHCID 23938PalladiumHCID 268679Methyl 5-methyl-4-nitrothiophene-2-carboxylate

Product 1

HCID 59640747Methyl 4-amino-5-methylthiophene-2-carboxylate

Sources & evidence

ORD record
ord-3ac162bcab474061b184960d89e51bf0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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