Dimethylamine → HCID 668793, compound

HRID 1030205Notes

Reaction equation

HRID 1030205 reaction equation
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9](Cl)(=[O:11])=[O:10])=[CH:5][CH:4]=1.[CH3:13][NH:14][CH3:15]>O1CCCC1>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([S:9]([N:14]([CH3:15])[CH3:13])(=[O:11])=[O:10])=[CH:5][CH:4]=1

Participants

4

Reactant 2

HCID 674DimethylamineHCID 74014-Methoxybenzenesulfonyl chloride

Product 1

HCID 668793HCID 668793, compound

Reagents, catalysts & solvents 1

HCID 8028TetrahydrofuranSolvent

Conditions

Temperature
50 °C

Procedure

To an ice-cooled solution of 4-methoxybenzenesulfonyl chloride (25 g) in tetrahydrofuran (25 ml) was added dimethylamine (50% solution in water, 25 ml). After addition was complete, the mixture was stirred at 50° C. for 30 minutes. The reaction mixture was concentrated to give 4-methoxy-N,N-dimethylbenzenesulfonamide (38 g).

Workup

  1. additionAfter addition
  2. concentrationThe reaction mixture was concentrated

Sources & evidence

ORD record
ord-35f86d989bd9443b827f0b008c1c2224
Source dataset
uspto-grants-1992_04
Patent number
US05104890

Reaction notes

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