Benzyl Alcohol → HCID 14879100, compound

HRID 1030300Notes

Reaction equation

HRID 1030300 reaction equation
[H-].[Na+].[C:3]1([C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[C:19](S(C)(=O)=O)[CH:18]=[C:17]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=4)[N:16]=3)[CH:12]=[CH:11][CH:10]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1.[CH2:31]([OH:38])[C:32]1[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=1>CN(C)C=O>[C:3]1([C:9]2[N:14]=[C:13]([C:15]3[CH:20]=[C:19]([O:38][CH2:31][C:32]4[CH:37]=[CH:36][CH:35]=[CH:34][CH:33]=4)[CH:18]=[C:17]([C:25]4[CH:30]=[CH:29][CH:28]=[CH:27][N:26]=4)[N:16]=3)[CH:12]=[CH:11][CH:10]=2)[CH:8]=[CH:7][CH:6]=[CH:5][CH:4]=1

Participants

5

Reactant 3

HCID 244Benzyl AlcoholHCID 24758Sodium hydrideHCID 19899502HCID 19899502, compound

Product 1

HCID 14879100HCID 14879100, compoundYield 85%

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

Sodium hydride (60% content, oil dispersion, 0.8 g) was added to a mixture of 6-phenyl-4'-methanesulfonyl-2,2':6',2"-terpyridine (4.67 g, 0.015 mol), benzyl alcohol (1.08 g, 0.010 mol) and N,N-dimethylformamide (0.1 liter) over a period of 10 minutes. The reaction solution was refluxed for 6 hours and then processed in the same manner as in Example 1, whereby 2.88 g of the above-entitled product (T-21) was obtained. Yield: 85%. m.p. 182° C.

Workup

  1. temperatureThe reaction solution was refluxed for 6 hours

Sources & evidence

ORD record
ord-927f7a2478d64fafb40e66f18b2a0985
Source dataset
uspto-grants-1992_04
Patent number
US05104988

Reaction notes

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