Hydrochloric Acid → HCID 19822262, compound

HRID 1030388Notes

Reaction equation

HRID 1030388 reaction equation
[OH:1][C:2]1[C:3]([CH3:40])=[C:4]2[C:9](=[C:10]([CH3:13])[C:11]=1[CH3:12])[O:8][C:7]([CH2:15][O:16][C:17]1[CH:38]=[CH:37][C:20]([CH2:21][CH:22]3[S:26][C:25](=[O:27])[N:24]([CH2:28][C:29]([O:31]C(C)(C)C)=[O:30])[C:23]3=[O:36])=[CH:19][CH:18]=1)([CH3:14])[CH2:6][C:5]2=[O:39].Cl>O1CCOCC1>[OH:1][C:2]1[C:3]([CH3:40])=[C:4]2[C:9](=[C:10]([CH3:13])[C:11]=1[CH3:12])[O:8][C:7]([CH2:15][O:16][C:17]1[CH:18]=[CH:19][C:20]([CH2:21][CH:22]3[S:26][C:25](=[O:27])[N:24]([CH2:28][C:29]([OH:31])=[O:30])[C:23]3=[O:36])=[CH:37][CH:38]=1)([CH3:14])[CH2:6][C:5]2=[O:39]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19822247HCID 19822247, compound

Product 1

HCID 19822262HCID 19822262, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 350 mg of t-butyl α-{5-[4-(6-hydroxy-2,5,7,8-tetramethyl-4-oxochroman-2-ylmethoxy)benzyl]-2,4-dioxothiazolidin-3yl}acetate (prepared as described in Example 49) and 4 ml of a 4N dioxane solution of hydrogen chloride was treated in the same manner described in Example 61, to give the title compound as a pale yellow powder, softening at 60°-70° C.

Workup

  1. additionwas treated in the same manner

Sources & evidence

ORD record
ord-33e89c85642c4ffca71378df16a9274f
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

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