Hydrochloric Acid → HCID 19822238, compound

HRID 1030393Notes

Reaction equation

HRID 1030393 reaction equation
C([O:5][C:6]([CH2:8][O:9][C:10]1[C:11]([CH3:56])=[C:12]2[C:17](=[C:18]([CH3:21])[C:19]=1[CH3:20])[O:16][C:15]([CH2:23][O:24][C:25]1[CH:54]=[CH:53][C:28]([CH2:29][C:30]3([CH2:45][C:46]([O:48]C(C)(C)C)=[O:47])[S:34][C:33](=[O:35])[N:32]([CH2:36][C:37]([O:39]C(C)(C)C)=[O:38])[C:31]3=[O:44])=[CH:27][CH:26]=1)([CH3:22])[CH2:14][C:13]2=[O:55])=[O:7])(C)(C)C.Cl>O1CCOCC1>[C:6]([CH2:8][O:9][C:10]1[C:11]([CH3:56])=[C:12]2[C:17](=[C:18]([CH3:21])[C:19]=1[CH3:20])[O:16][C:15]([CH2:23][O:24][C:25]1[CH:26]=[CH:27][C:28]([CH2:29][C:30]3([CH2:45][C:46]([OH:48])=[O:47])[S:34][C:33](=[O:35])[N:32]([CH2:36][C:37]([OH:39])=[O:38])[C:31]3=[O:44])=[CH:53][CH:54]=1)([CH3:22])[CH2:14][C:13]2=[O:55])([OH:7])=[O:5]

Participants

4

Reactant 2

HCID 313Hydrochloric AcidHCID 19822178HCID 19822178, compound

Product 1

HCID 19822238HCID 19822238, compound

Reagents, catalysts & solvents 1

HCID 312751,4-DioxaneSolvent

Procedure

A mixture of 340 mg of di-t-butyl α,α'-{5-[4-(6-t-butoxycarbonylmethoxy-2,5,7,8-tetramethyl -4-oxochroman-2-ylmethoxy)benzyl]-2,4-dioxothiazolidine-3,5-diyl}diacetate (prepared as described in Example 50) and 4 ml of a 4N dioxane solution of hydrogen chloride was treated in the same manner described in Example 61, to give the title compound as a pale yellow powder, softening at 105°-110° C.

Workup

  1. additionwas treated in the same manner

Sources & evidence

ORD record
ord-467a7b2390514bcca84a7963bccdaf86
Source dataset
uspto-grants-1992_04
Patent number
US05104888

Reaction notes

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