反应详情

温度

60 °C

120 ml of ethanol and 120 ml of water were added to 23.1 g of 3-nitro-4-phenoxyphenol, and the mixture was made into a solution by heating at 60° C. 2.3 ml of 4N hydrochloric acid was added thereto. While maintaining the reaction temperature at 65°-70° C., 16.8 g of an iron powder was added thereto in portions in 20 minutes. Stirring was conducted for 30 minutes at the same temperature. The reaction mixture was hot-filtered. 50 ml of water was added to the filtrate and the mixture was allowed to stand. The resulting crystal was collected by filtration to obtain 16.5 g (yield: 82.1%) of 3-amino-4-phenoxyphenol having a melting point of 156°-157° C.

1. temperatureWhile maintaining the reaction temperature at 65°-70° C.
2. waitwas conducted for 30 minutes at the same temperature
3. filtrationThe reaction mixture was hot-filtered
4. addition50 ml of water was added to the filtrate
5. filtrationThe resulting crystal was collected by filtration