Sodium hydride → HCID 14722420, compound

HRID 1031739Notes

Reaction equation

HRID 1031739 reaction equation
Cl[CH2:2][CH2:3][CH2:4][C:5]([NH:7][C:8]1[C:13](=[O:14])[C:12]2[CH:15]=[C:16]([O:24][C:25]3[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=3)[C:17]([NH:19][S:20]([CH3:23])(=[O:22])=[O:21])=[CH:18][C:11]=2[O:10][CH:9]=1)=[O:6].[H-].[Na+]>CN(C)C=O>[CH3:23][S:20]([NH:19][C:17]1[C:16]([O:24][C:25]2[CH:30]=[CH:29][CH:28]=[CH:27][CH:26]=2)=[CH:15][C:12]2[C:13](=[O:14])[C:8]([N:7]3[CH2:2][CH2:3][CH2:4][C:5]3=[O:6])=[CH:9][O:10][C:11]=2[CH:18]=1)(=[O:22])=[O:21]

Participants

4

Reactant 2

HCID 24758Sodium hydrideHCID 14722419HCID 14722419, compound

Product 1

HCID 14722420HCID 14722420, compound

Reagents, catalysts & solvents 1

HCID 6228DimethylformamideSolvent

Procedure

3-(4-Chlorobutyrylamino)-7-methylsulfonylamino-6-phenoxy-4H-1-benzopyran-4-one was reacted with sodium hydride in N,N-dimethylformamide to obtain 7-methylsulfonylamino-3-(2-oxopyrrolidin-1-yl)-6-phenoxy-4H-1-benzopyran-4-one.

Sources & evidence

ORD record
ord-83179bd456ed4d7c82cb6c08896210ca
Source dataset
uspto-grants-1990_09
Patent number
US04954518

Reaction notes

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