Methylamine → HCID 69553959, compound

HRID 1032233Notes

Reaction equation

HRID 1032233 reaction equation
[CH3:1][NH2:2].[F:3][C:4]([F:14])([F:13])[C:5]1[CH:12]=[CH:11][C:8]([CH:9]=O)=[CH:7][CH:6]=1.[O-]S([O-])(=O)=O.[Mg+2]>C1C=CC=CC=1>[F:3][C:4]([F:14])([F:13])[C:5]1[CH:12]=[CH:11][C:8]([CH:9]=[CH:1][NH2:2])=[CH:7][CH:6]=1

Participants

5

Reactant 3

HCID 6329MethylamineHCID 24083Sulfuric acid magnesium salt (1:1)HCID 679964-(Trifluoromethyl)benzaldehyde

Product 1

HCID 69553959HCID 69553959, compound

Reagents, catalysts & solvents 1

HCID 241BenzeneSolvent

Procedure

Methylamine was passed into a solution of about 10.1 g of 4-(trifluoromethyl)benzaldehyde in about 100 ml of benzene over MgSO4 for four hours with stirring. The solution was filtered, and then the solvent was evaporated to give N-[4-(trifluoromethyl)benzylidene]methylamine as an oil. This was taken up in benzene and catalytically (5% Pd/C) hydrogenated to give the title product.

Workup

  1. filtrationThe solution was filtered
  2. customthe solvent was evaporated

Sources & evidence

ORD record
ord-70e7249dd32048f3900a3f09cd74f261
Source dataset
uspto-grants-1990_09
Patent number
US04957533

Reaction notes

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