Triphenylphosphine → (5 Chlorobenzoxazol-2-yl methyl)triphenylphosphonium bromide

HRID 1032323Notes

Reaction equation

HRID 1032323 reaction equation
[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][Br:11])=[N:7][C:6]=2[CH:12]=1.[C:13]1([P:19]([C:26]2[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=2)[C:20]2[CH:25]=[CH:24][CH:23]=[CH:22][CH:21]=2)[CH:18]=[CH:17][CH:16]=[CH:15][CH:14]=1>CC#N.CCOCC>[Br-:11].[Cl:1][C:2]1[CH:3]=[CH:4][C:5]2[O:9][C:8]([CH2:10][P+:19]([C:20]3[CH:21]=[CH:22][CH:23]=[CH:24][CH:25]=3)([C:26]3[CH:31]=[CH:30][CH:29]=[CH:28][CH:27]=3)[C:13]3[CH:14]=[CH:15][CH:16]=[CH:17][CH:18]=3)=[N:7][C:6]=2[CH:12]=1

Participants

5

Reactant 2

HCID 11776TriphenylphosphineHCID 127459452-(Bromomethyl)-5-chlorobenzo[d]oxazole

Product 1

HCID 23055263(5 Chlorobenzoxazol-2-yl methyl)triphenylphosphonium bromide

Reagents, catalysts & solvents 2

HCID 3283Diethyl EtherSolventHCID 6342AcetonitrileSolvent

Procedure

A solution of the bromide (500 mg) (Step 3) and triphenylphosphine (740 mg) in CH3CN (5 mL) was stirred at room temperature overnight. The reaction mixture was diluted with Et2O (20 mL), stirred for 30 min, and filtered to give the title compound as a white solid.

Workup

  1. filtrationfiltered

Sources & evidence

ORD record
ord-07367f49a302496b9fb474ee9f3acff1
Source dataset
uspto-grants-1990_09
Patent number
US04957932

Reaction notes

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