Methyl Acrylate → HCID 14838405, compound

HRID 1032385Notes

Reaction equation

HRID 1032385 reaction equation
[CH3:1][O:2][C:3](=[O:6])[CH:4]=[CH2:5].[NH2:7][CH2:8][CH:9]1[CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[O:11][CH2:10]1>CO>[CH3:1][O:2][C:3]([CH2:4][CH2:5][N:7]([CH2:5][CH2:4][C:3]([O:2][CH3:1])=[O:6])[CH2:8][CH:9]1[CH2:18][C:17]2[C:12](=[CH:13][CH:14]=[CH:15][CH:16]=2)[O:11][CH2:10]1)=[O:6]

Participants

4

Reactant 2

HCID 7294Methyl AcrylateHCID 4962852Chroman-3-ylmethanamine

Product 1

HCID 14838405HCID 14838405, compoundYield 95%

Reagents, catalysts & solvents 1

HCID 887MethanolSolvent

Procedure

3.03 g (35.2 mmol) of acrylic acid methyl ester are added to a solution of 2.61 g (16 mmol) of 3-aminomethylchroman in 20 ml of methanol. The reaction solution is stirred for 16 hours at 50° and, after cooling, is concentrated by evaporation in vacuo. 5.1 g (95%) of N,N-bis(2-methoxycarbonylethyl)-N-(chroman-3-ylmethyl)-amine are obtained in the form of a reddish oil.

Workup

  1. temperatureafter cooling
  2. concentrationis concentrated by evaporation in vacuo

Sources & evidence

ORD record
ord-3f512efba59440a09deb72bc63c4b683
Source dataset
uspto-grants-1990_09
Patent number
US04957928

Reaction notes

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