HRID1032544

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID13629308

未命名化合物

PRODUCTS

生成物

HCID19354434

未命名化合物

收率 87.8%

AUXILIARIES

试剂、催化剂与溶剂

催化剂HCID935

Nickel

溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

20.2 g of 2-(7-nitro-1H-indazol-4-yl)-acetonitrile in 750 ml of tetrahydrofuran is hydrogenated in the presence of 20.0 g of Raney nickel. The product is recrystallized from tetrahydrofuran/hexane, yielding 15.1 g of 2-(7-amino-1H-indazol-4-yl)acetonitrile, mp 164°-165° C.

WORKUP

后处理

customThe product is recrystallized from tetrahydrofuran/hexane