反应详情

温度

100 °C

The product of part (a) (75.0 g) in 2 L water was heated on a steam bath, and 200 g potassium permanganate was added portion-wise. The reaction mixture was heated at 100° C. for three days and then filtered to remove manganese oxide. The filtrate was concentrated in vacuo and the residue dried to give 36.1 g of 2-fluoro-4-(4pyridinyl)benzoic acid.

1. filtrationfiltered
2. customto remove manganese oxide
3. concentrationThe filtrate was concentrated in vacuo
4. customthe residue dried