Diethylamine → HCID 4418042, compound

HRID 1033171Notes

Reaction equation

HRID 1033171 reaction equation
Cl[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1.[CH2:11]([NH:13][CH2:14][CH3:15])[CH3:12]>>[CH2:11]([N:13]([CH2:14][CH3:15])[C:2]1[CH:7]=[CH:6][C:5]([N+:8]([O-:10])=[O:9])=[CH:4][N:3]=1)[CH3:12]

Participants

3

Reactant 2

HCID 8021DiethylamineHCID 783082-Chloro-5-nitropyridine

Product 1

HCID 4418042HCID 4418042, compound

Procedure

Following Intermediate Method 5, the reaction of 2-chloro-5-nitropyridine, (XXII) with diethylamine produces 2-diethylamino-5-nitropyridine, (XXII). The reduction of this compound (XXII) with iron powder in aqueous hydrochloric acid and ethanol yields 5-amino-2-diethylaminopyridine, (XXIII).

Sources & evidence

ORD record
ord-93650fbb3a1b4ba5a55583b70df0acb0
Source dataset
uspto-grants-1994_05
Patent number
US05310724

Reaction notes

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