Dimethyl Sulfoxide → 5-Fluoro-6-(4-methylpiperazinyl)isatin

HRID 103406Notes

Reaction equation

HRID 103406 reaction equation
[CH3:14][N:15]1[CH2:16][CH2:17][NH:18][CH2:19][CH2:20]1.[CH3:21][S:22](=[O:23])[CH3:24].[CH3:25][CH2:26][O:27][C:28](=[O:29])[CH3:30].[F:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][c:10]1[F:11])[NH:7][C:6](=[O:12])[C:5]2=[O:13]>>[F:1][c:2]1[cH:3][c:4]2[c:8]([cH:9][c:10]1[N:18]1[CH2:17][CH2:16][N:15]([CH3:14])[CH2:20][CH2:19]1)[NH:7][C:6](=[O:12])[C:5]2=[O:13]

Participants

5

Reactant 4

HCID 679Dimethyl SulfoxideHCID 8857Ethyl AcetateHCID 531671-MethylpiperazineHCID 19263085,6-difluoro-2,3-dihydro-1H-indole-2,3-dione

Product 1

HCID 193907095-Fluoro-6-(4-methylpiperazinyl)isatin

Sources & evidence

ORD record
ord-4cd5698557c64bc89058dfef4381bd65
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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