HCID 3714618, compound → HCID 3714620, compound

HRID 1034335Notes

Reaction equation

HRID 1034335 reaction equation
[CH2:1]([N:5]([CH2:19][CH2:20][CH2:21][C:22]1[CH:27]=[CH:26][CH:25]=[CH:24][CH:23]=1)[S:6]([C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]([N+:16]([O-])=O)[CH:10]=1)(=[O:8])=[O:7])[CH2:2][CH2:3][CH3:4].[H][H]>[Pt].C(O)C>[CH2:1]([N:5]([CH2:19][CH2:20][CH2:21][C:22]1[CH:23]=[CH:24][CH:25]=[CH:26][CH:27]=1)[S:6]([C:9]1[CH:14]=[CH:13][C:12]([OH:15])=[C:11]([NH2:16])[CH:10]=1)(=[O:8])=[O:7])[CH2:2][CH2:3][CH3:4]

Participants

5

Reactant 2

HCID 3714618HCID 3714618, compoundHCID 178418361HCID 178418361, compound

Product 1

HCID 3714620HCID 3714620, compoundYield 98.9%

Reagents, catalysts & solvents 2

HCID 23939PlatinumCatalystHCID 702EthanolSolvent

Procedure

A mixture of 13.16 g N-butyl-N-(3'-phenylpropyl)-4-hydroxy-3-nitrobenzenesulfonamide, 2 g 1 wt % platinum on alumina, and 200 ml ethanol was stirred for 22 hours at room temperature in a bomb charged with 800 psi of hydrogen. The solution was filtered and concentrated to give 12.02 g N-butyl-N-(3'-phenylpropyl)-3-amino-4-hydroxybenzensulfonamide.

Workup

  1. filtrationThe solution was filtered
  2. concentrationconcentrated

Sources & evidence

ORD record
ord-fd0a4dd1c9784b52b4acb02a8982fc26
Source dataset
uspto-grants-1994_05
Patent number
US05314998

Reaction notes

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