Methanol → 6-(3-(tert-butylcarbamoyl)phenyl)-2-(4-fluorophenyl)-N-methylimidazo[1,2-a]pyridine-3-carboxamide

HRID 103478Notes

Reaction equation

HRID 103478 reaction equation
[CH3:35][C:36]([CH3:37])([CH3:38])[NH2:39].[CH3:64][OH:65].[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][c:13](-[c:16]4[cH:17][c:18]([C:19](=[O:20])[OH:21])[cH:22][cH:23][cH:24]4)[cH:14][cH:15]3)[c:25]2[C:26]([NH:27][CH3:28])=[O:29])[cH:6][cH:7]1.[O:30]=[CH:31][N:32]([CH3:33])[CH3:34].[P-:40]([F:41])([F:42])([F:43])([F:44])([F:45])[F:46].[n:47]1([O:48][C:49]([N:50]([CH3:51])[CH3:52])=[N+:53]([CH3:54])[CH3:55])[c:56]2[n:57][cH:58][cH:59][cH:60][c:61]2[n:62][n:63]1>>[F:1][c:2]1[cH:3][cH:4][c:5](-[c:8]2[n:9][c:10]3[n:11]([cH:12][c:13](-[c:16]4[cH:17][c:18]([C:19](=[O:20])[NH:39][C:36]([CH3:35])([CH3:37])[CH3:38])[cH:22][cH:23][cH:24]4)[cH:14][cH:15]3)[c:25]2[C:26]([NH:27][CH3:28])=[O:29])[cH:6][cH:7]1

Participants

7

Reactant 6

HCID 887MethanolHCID 6228DimethylformamideHCID 6385Tert-ButylamineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 592336813-(2-(4-Fluorophenyl)-3-(methylcarbamoyl)imidazo[1,2-a]pyridin-6-yl)benzoic acid

Product 1

HCID 592336576-(3-(tert-butylcarbamoyl)phenyl)-2-(4-fluorophenyl)-N-methylimidazo[1,2-a]pyridine-3-carboxamide

Sources & evidence

ORD record
ord-738de359bbe941fbbe8750af984889b9
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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