4-Aminopyridine → 1-[4-(methylamino)-6-(4-pyridinylamino)-1,3,5-triazin-2-yl]-N-{[2-(trifluoromethyl)phenyl]methyl}-4-piperidinecarboxamide
Reaction equation
[CH3:46][C:47]#[N:48].[CH:30]([N:31]([CH:32]([CH3:33])[CH3:34])[CH2:35][CH3:36])([CH3:37])[CH3:38].[Cl:1][c:2]1[n:3][c:4]([N:10]2[CH2:11][CH2:12][CH:13]([C:16](=[O:17])[NH:18][CH2:19][c:20]3[c:21]([C:26]([F:27])([F:28])[F:29])[cH:22][cH:23][cH:24][cH:25]3)[CH2:14][CH2:15]2)[n:5][c:6]([NH:8][CH3:9])[n:7]1.[NH2:39][c:40]1[cH:41][cH:42][n:43][cH:44][cH:45]1>>[c:2]1([NH:39][c:40]2[cH:41][cH:42][n:43][cH:44][cH:45]2)[n:3][c:4]([N:10]2[CH2:11][CH2:12][CH:13]([C:16](=[O:17])[NH:18][CH2:19][c:20]3[c:21]([C:26]([F:27])([F:28])[F:29])[cH:22][cH:23][cH:24][cH:25]3)[CH2:14][CH2:15]2)[n:5][c:6]([NH:8][CH3:9])[n:7]1Participants
5
Reactant 4
Product 1
Sources & evidence
- ORD record
- ord-f21fb6f19ee2482e9e0012c02abb8740
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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