反应详情

The compound 3 (1.28 g, 7.18 mmol) is mixed with triethoxysilane (3.6 ml). The Karstedt catalyst is added very slowly in a catalytic amount (10 drops). The reaction takes place at 45° C. over three days. The product is purified by flash chromatography (100% AcOEt) to give a brown liquid (2.4 g, 7 mmol, 97%).

1. customat 45° C.
2. customover three days
3. customThe product is purified by flash chromatography (100% AcOEt)