N,N-Diethyl-p-phenylenediamine → HCID 57710357, compound

HRID 1038677Notes

Reaction equation

HRID 1038677 reaction equation
Cl[C:2]1[N:7]=[CH:6][N:5]=[C:4]([NH:8][CH3:9])[CH:3]=1.[NH2:10][C:11]1[CH:21]=[CH:20][C:14]([N:15]([CH2:18][CH3:19])[CH2:16][CH3:17])=[CH:13][CH:12]=1>>[CH2:18]([N:15]([CH2:16][CH3:17])[C:14]1[CH:20]=[CH:21][C:11]([NH:10][C:2]2[CH:3]=[C:4]([NH:8][CH3:9])[N:5]=[CH:6][N:7]=2)=[CH:12][CH:13]=1)[CH3:19]

Participants

3

Reactant 2

HCID 7120N,N-Diethyl-p-phenylenediamineHCID 3094796-chloro-N-methylpyrimidin-4-amine

Product 1

HCID 57710357HCID 57710357, compound

Procedure

The title compound is prepared analogously as described in Example 105A from (6-chloro-pyrimidin-4-yl)-methyl-amine and 4-amino-N,N-diethylaniline. The ethyl acetate layer is dried over Na2SO4 and evaporated in vacuo. The residue is suspended in CH2Cl2, filtered off and dried to afford the title compound.

Workup

  1. customThe title compound is prepared analogously
  2. dry with materialThe ethyl acetate layer is dried over Na2SO4
  3. customevaporated in vacuo
  4. filtrationfiltered off
  5. customdried

Sources & evidence

ORD record
ord-3c236ae5c4004f63a5ee7b8193ec5493
Source dataset
uspto-grants-2013_10
Patent number
US08552002B2

Reaction notes

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