1-Methylpiperazine → HCID 67264017, compound

HRID 1041178Notes

Reaction equation

HRID 1041178 reaction equation
[N+:1]([C:4]1[CH:5]=[CH:6][C:7]2[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9][C:8]=2[CH:15]=1)([O-:3])=[O:2].[CH3:16][N:17]1[CH2:22][CH2:21][NH:20][CH2:19][CH2:18]1>>[CH3:16][N:17]1[CH2:22][CH2:21][N:20]([CH:11]2[CH2:10][CH2:9][C:8]3[CH:15]=[C:4]([N+:1]([O-:3])=[O:2])[CH:5]=[CH:6][C:7]=3[CH2:13][CH2:12]2)[CH2:19][CH2:18]1

Participants

3

Reactant 2

HCID 531671-MethylpiperazineHCID 457903192-Nitro-8,9-dihydro-5H-benzo[7]annulen-7(6H)-one

Product 1

HCID 67264017HCID 67264017, compound

Procedure

1-Methyl-4-(2-nitro-6,7,8,9-tetrahydro-5H-benzocyclohepten-7-yl)-piperazine was prepared from 2-nitro-5,6,8,9-tetrahydrobenzocyclohepten-7-one and 1-methyl piperazine in a similar manner to Example 178a. Product was isolated as a brown solid.

Workup

  1. customProduct was isolated as a brown solid

Sources & evidence

ORD record
ord-cbae829e06ee4e4294842e5334c325a2
Source dataset
uspto-grants-2013_10
Patent number
US08552186B2

Reaction notes

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