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HRID1042492

反应详情

EQUATION

反应方程式

HRID 1042492 的结构方程式

REACTANTS

反应物

2
结构：[Li+].[OH-]
HCID3939

Lithium hydroxide anhydrous

HLiO

结构：CCCCOc1cc(F)ccc1C=CC(=O)OC
HCID66856235

未命名化合物

PRODUCTS

生成物

1
结构：CCCCOc1cc(F)ccc1C=CC(=O)O
HCID66856504

未命名化合物

收率 101.5%

AUXILIARIES

试剂、催化剂与溶剂

2
结构：CO
溶剂HCID887

Methanol

CH4O

结构：C1CCOC1
溶剂HCID8028

Tetrahydrofuran

C4H8O

PROCEDURE

实验过程

3-(2-Butoxy-4-fluoro-phenyl)-acrylic acid methyl ester (121 mg) was reacted with 1N LiOH (5 ml) in THF and CH3OH for 2 hrs as described above to yield title compound (116 mg).