Iodoethane → HCID 12392672, compound

1-ethylimidazole (4.81 g, 50 mmol, Sigma-Aldrich, 99%) in 50 mL ethyl acetate was cooled to 0° C. in an ice bath. Once cool, iodoethane (8.69 g, 55.7 mmol, Sigma-Aldrich, 99%) was added dropwise via an addition funnel. The solution was allowed to warm slowly to room temperature then stirred overnight. The precipitate was filtered off and washed with diethyl ether. The filtrate was collected and an additional 8.96 g (57.4 mmol) iodoethane was added and stirring continued at room temperature for 6 days. The solution was filtered again and the residue was washed with diethyl ether. The combined solids were dried overnight under high vacuum yielding 9.76 g white solids (38.7 mmol, 77% yield) that were used without further purification.

1. temperatureOnce cool
2. filtrationThe precipitate was filtered off
3. washwashed with diethyl ether
4. customThe filtrate was collected
5. stirringstirring
6. waitcontinued at room temperature for 6 days
7. filtrationThe solution was filtered again
8. washthe residue was washed with diethyl ether
9. customThe combined solids were dried overnight under high vacuum

ORD record

ord-1f309f1f8b1b41dfae0641bbae72fa81

Source dataset

uspto-grants-2013_10

DOI

10.6084/m9.figshare.5104873.v1

Patent number

US08562942B2