Catechol → Adamantane

HRID 1044335Notes

Reaction equation

C1(C(=CC=CC=1)O)O.[C:9]12(O)[CH2:18][CH:13]3[CH2:14][CH:15]([CH2:17][C:11](O)([CH2:12]3)[CH2:10]1)[CH2:16]2>>[CH:9]12[CH2:18][CH:13]3[CH2:14][CH:15]([CH2:17][CH:11]([CH2:12]3)[CH2:10]1)[CH2:16]2

Participants

Reactant 2

HCID 289Catechol

HCID 5738291,3-Adamantanediol

Product 1

HCID 9238Adamantane

Procedure

Reaction of catechol with 1,3-adamantane-diol according to the method described by Lu et al (Lu et al. J Med Chem 2005, 48 (14), 4576-4585) gave the adduct 10 in reasonable yield.

Sources & evidence

ORD record: ord-aed952d387894b8fbb04f8c20887eaaf
Source dataset: uspto-grants-2013_10
DOI: 10.6084/m9.figshare.5104873.v1
Patent number: US08563590B2

Reaction notes

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