反应详情

To a suspension of 10.2 g (67 mmol) of the product obtained in Step A above in 150 ml of CH2Cl2 there are added 28 ml (0.201 mol) of triethylamine. 13.9 ml (0.147 mol) of acetic anhydride are added dropwise and the solution is stirred overnight at ambient temperature. After washing 3 times with water and then with brine, the organic phase is dried over MgSO4 and evaporated. The solid obtained is taken up in isopropyl ether and then filtered and dried to yield the title compound.

1. washAfter washing 3 times with water
2. dry with materialwith brine, the organic phase is dried over MgSO4
3. customevaporated
4. customThe solid obtained
5. filtrationfiltered
6. customdried