Hydrazine hydrate (1:1) → HCID 58242743, compound

HRID 1047313Notes

Reaction equation

HRID 1047313 reaction equation
O.[NH2:2][NH2:3].[F:4][C:5]([F:19])([F:18])[C:6]([F:17])([F:16])[C:7](=O)[CH2:8][C:9](=O)[C:10]([CH3:13])([CH3:12])[CH3:11]>C(O)C>[C:10]([C:9]1[CH:8]=[C:7]([C:6]([F:17])([F:16])[C:5]([F:19])([F:18])[F:4])[NH:3][N:2]=1)([CH3:13])([CH3:12])[CH3:11]

Participants

4

Reactant 2

HCID 24654Hydrazine hydrate (1:1)HCID 750674H,4H-Perfluoro-6,6-dimethylheptane-3,5-dione

Product 1

HCID 58242743HCID 58242743, compoundYield 79.5%

Reagents, catalysts & solvents 1

HCID 702EthanolSolvent

Procedure

At room temperature, hydrazine hydrate (2.06 g) is added to a solution of 1,1,1,2,2-pentafluoro-6,6-dimethylheptane-3,5-dione (10.1 g) in ethanol (100 ml). The reaction mixture is stirred at room temperature overnight. After removal of the solvents under reduced pressure, 3-tert-butyl-5-(pentafluoroethyl)-1H-pyrazole (7.9 g, 79%) is obtained.

Workup

  1. customAfter removal of the solvents under reduced pressure

Sources & evidence

ORD record
ord-4a2c7da832f04340ba0f85ef63d0ae1f
Source dataset
uspto-grants-2013_10
Patent number
US08569509B2

Reaction notes

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