Dimethylformamide → (RS)-N-(4-cyano-benzyl)-2-(4-ethoxy-phenyl)-2-methoxy-acetamide

HRID 104893Notes

Reaction equation

HRID 104893 reaction equation
[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][C:9]([CH:10]([O:11][CH3:12])[c:13]2[cH:14][cH:15][c:16]([OH:19])[cH:17][cH:18]2)=[O:20])[cH:21][cH:22]1.[C:23](=[O:24])([O-:25])[O-:26].[CH2:28]([CH3:29])[I:30].[Cs+:27].[Cs+:31].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([CH2:7][NH:8][C:9]([CH:10]([O:11][CH3:12])[c:13]2[cH:14][cH:15][c:16]([O:19][CH2:28][CH3:29])[cH:17][cH:18]2)=[O:20])[cH:21][cH:22]1

Participants

6

Reactant 5

HCID 6228DimethylformamideHCID 6340IodoethaneHCID 19660Carbonate IonHCID 104967Cesium cation2×HCID 21905457(RS)-N-(4-cyano-benzyl)-2-(4-hydroxy-phenyl)-2-methoxy-acetamide

Product 1

HCID 21904945(RS)-N-(4-cyano-benzyl)-2-(4-ethoxy-phenyl)-2-methoxy-acetamide

Sources & evidence

ORD record
ord-5ef6b9c9e53840dfbb3488373af2882c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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