反应详情

Intermediate 10 (78.5 g, 291 mmol) is dissolved in AcOH (850 mL). To the resulting suspension, NCS (42.9 g, 320 mmol) is added. The mixture is stirred at room temperature, after which it is evaporated to give a slurry. This slurry is taken up in water to give a suspension that is filtered. Resulting precipitate is dried in the vacuum oven and used as such.

1. customafter which it is evaporated
2. customto give a slurry
3. customto give a suspension that
4. filtrationis filtered
5. customResulting precipitate
6. customis dried in the vacuum oven