Tetrahydrofuran → (4-Phenylbicyclo[2.2.2]oct-1-yl)methanol

HRID 105174Notes

Reaction equation

HRID 105174 reaction equation
[Al+3:21].[CH2:26]1[O:27][CH2:28][CH2:29][CH2:30]1.[H-:20].[H-:23].[H-:24].[H-:25].[Li+:22].[c:1]1([C:7]23[CH2:8][CH2:9][C:10]([C:15](=[O:16])[O:17][CH2:18][CH3:19])([CH2:11][CH2:12]2)[CH2:13][CH2:14]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1>>[c:1]1([C:7]23[CH2:8][CH2:9][C:10]([CH2:15][OH:16])([CH2:11][CH2:12]2)[CH2:13][CH2:14]3)[cH:2][cH:3][cH:4][cH:5][cH:6]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 21627803Ethyl 4-phenylbicyclo[2.2.2]octane-1-carboxylate

Product 1

HCID 21675352(4-Phenylbicyclo[2.2.2]oct-1-yl)methanol

Sources & evidence

ORD record
ord-c3ffc432b20f4779b850061332e3b533
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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