反应详情

A mixture of methyl 2-phenyl-4,5,6,7-tetrahydrobenzo[d]thiazole-7-carboxylate (12.0 mg, 0.044 mmol) and LiOH.H2O (2.7 mg, 0.065 mmol) in THF/MeOH/H2O (1 mL, 3:1:1) was stirred at RT for 45 min. The mixture was acidified to pH=3 and extracted with DCM. The comb. org. layers were dried over MgSO4, and conc. in vacuo.

1. extractionextracted with DCM
2. dry with materiallayers were dried over MgSO4