反应详情

To a solution of tert-butyl 2-(3-cyano-1H-pyrazolo[3,4-c]pyridin-1-yl)acetate (663 mg, 2.40 mmol) in TFA (6 mL) was subjected to microwave irradiation at 140° C. for 90 min. The reaction mixture was concentrated in vacuo, the residual solid was suspended in MeOH and volatiles were removed again in vacuo. MS: 221.0 [M+H]+; tR (HPLC conditions d): 0.23 min.

1. customirradiation at 140° C. for 90 min
2. concentrationThe reaction mixture was concentrated in vacuo
3. customvolatiles were removed again in vacuo
4. custom0.23 min.