Tetrahydrofuran → 3-Benzyl-10-(2-fluorophenyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

HRID 105260Notes

Reaction equation

HRID 105260 reaction equation
[Al+3:2].[C:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)(=[O:14])[N:15]1[CH2:16][CH2:17][c:18]2[nH:19][c:20]3[cH:21][cH:22][cH:23][c:24](-[c:29]4[c:30]([F:35])[cH:31][cH:32][cH:33][cH:34]4)[c:25]3[c:26]2[CH2:27][CH2:28]1.[H-:1].[H-:4].[H-:5].[H-:6].[Li+:3].[O:36]1[CH2:37][CH2:38][CH2:39][CH2:40]1>>[CH2:7]([c:8]1[cH:9][cH:10][cH:11][cH:12][cH:13]1)[N:15]1[CH2:16][CH2:17][c:18]2[nH:19][c:20]3[cH:21][cH:22][cH:23][c:24](-[c:29]4[c:30]([F:35])[cH:31][cH:32][cH:33][cH:34]4)[c:25]3[c:26]2[CH2:27][CH2:28]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 223966933-Benzoyl-10-(2-fluorophenyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

Product 1

HCID 223967213-Benzyl-10-(2-fluorophenyl)-1,2,3,4,5,6-hexahydroazepino[4,5-b]indole

Sources & evidence

ORD record
ord-65513814d255469b8f9d168e8b280c68
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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