Ammonium → ethyl 7-(3,4-difluorobenzyl)-2-(trifluoromethyl)-2H-chromene-3-carboxylate
Reaction equation
[Br-:21].[CH2:34]1[O:35][CH2:36][CH2:37][CH2:38]1.[Cl-:32].[F:22][c:23]1[cH:24][c:25]([CH2:26][Zn+:27])[cH:28][cH:29][c:30]1[F:31].[I:1][c:2]1[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[O:9][CH:8]([C:12]([F:13])([F:14])[F:15])[C:7]([C:16](=[O:17])[O:18][CH2:19][CH3:20])=[CH:6]2.[NH4+:33]>>[c:2]1([CH2:26][c:25]2[cH:24][c:23]([F:22])[c:30]([F:31])[cH:29][cH:28]2)[cH:3][cH:4][c:5]2[c:10]([cH:11]1)[O:9][CH:8]([C:12]([F:13])([F:14])[F:15])[C:7]([C:16](=[O:17])[O:18][CH2:19][CH3:20])=[CH:6]2Participants
7
Sources & evidence
- ORD record
- ord-2204f98fb45844eda23b345fa9d085be
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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