Acetate → 2-Cyclopropyl-5-((2-(trimethylsilyl)ethoxy)methyl)-5H-pyrrolo[2,3-b]pyrazine-7-carbaldehyde
Reaction equation
[Br:1][c:2]1[n:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:13][O:14][CH2:15][CH2:16][Si:17]([CH3:18])([CH3:19])[CH3:20])[cH:9][c:10]2[CH:11]=[O:12].[CH3:46][c:47]1[cH:48][cH:49][cH:50][cH:51][cH:52]1.[CH:21]1([B:24]([OH:25])[OH:26])[CH2:22][CH2:23]1.[CH:27]1([P:28]([CH:29]2[CH2:30][CH2:31][CH2:32][CH2:33][CH2:34]2)[CH:35]2[CH2:36][CH2:37][CH2:38][CH2:39][CH2:40]2)[CH2:41][CH2:42][CH2:43][CH2:44][CH2:45]1.[O-:55][C:56]([CH3:57])=[O:58].[O-:59][C:60]([CH3:61])=[O:62].[OH2:53].[Pd+2:54]>>[c:2]1([CH:21]2[CH2:22][CH2:23]2)[n:3][c:4]2[c:5]([n:6][cH:7]1)[n:8]([CH2:13][O:14][CH2:15][CH2:16][Si:17]([CH3:18])([CH3:19])[CH3:20])[cH:9][c:10]2[CH:11]=[O:12]Participants
8
Reactant 7
Product 1
Sources & evidence
- ORD record
- ord-80586b36f5594d43a6472dc89725043f
- Source dataset
- Training data from https://doi.org/10.1039/C8SC04228D (2/10)
Reaction notes
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