Tetrahydrofuran → 1-Benzyl-4-phenyl-3-pyrrolidinemethanol

HRID 105485Notes

Reaction equation

HRID 105485 reaction equation
[Al+3:34].[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([C:19](=[O:20])[N:21]2[CH:22]([c:23]3[cH:24][cH:25][cH:26][cH:27][cH:28]3)[CH2:29][O:30][C:31]2=[O:32])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1.[CH2:39]1[O:40][CH2:41][CH2:42][CH2:43]1.[H-:33].[H-:36].[H-:37].[H-:38].[Li+:35]>>[CH2:1]([c:2]1[cH:3][cH:4][cH:5][cH:6][cH:7]1)[N:8]1[CH2:9][CH:10]([CH2:19][OH:20])[CH:11]([c:13]2[cH:14][cH:15][cH:16][cH:17][cH:18]2)[CH2:12]1

Participants

6

Reactant 5

HCID 8028TetrahydrofuranHCID 28486Lithium ionHCID 104727Aluminum CationHCID 166653Hydride4×HCID 229124353-(1-Benzyl-4-phenylpyrrolidine-3-carbonyl)-4-phenyl-1,3-oxazolidin-2-one

Product 1

HCID 219127561-Benzyl-4-phenyl-3-pyrrolidinemethanol

Sources & evidence

ORD record
ord-bc9ac6e3052e4b17bad9a57c8ca9f676
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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