Ethyl Acetate → HCID 88018871, compound

HRID 1058578Notes

Reaction equation

HRID 1058578 reaction equation
CO[C:3]([C:5]1[C:9]2[CH:10]=[CH:11][CH:12]=[CH:13][C:8]=2[O:7][C:6]=1[C:14]([O:16]CC1C=CC=CC=1)=[O:15])=[O:4].[C:24](OCC)(=[O:26])C>[Pd]>[CH3:24][O:26][C:11]1[CH:12]=[CH:13][C:8]2[O:7][CH:6]([C:14]([OH:16])=[O:15])[C:5](=[C:3]=[O:4])[C:9]=2[CH:10]=1

Participants

4

Reactant 2

HCID 8857Ethyl AcetateHCID 18668881HCID 18668881, compound

Product 1

HCID 88018871HCID 88018871, compoundYield 91%

Reagents, catalysts & solvents 1

HCID 23938PalladiumCatalyst

Procedure

To a solution of benzyl methoxy-carbonylbenzofuran-2-carboxylate (0.144 g, 0.409 mmol) in ethyl acetate (20 mL) was added 10% palladium on carbon (0.072 g, 50% w/w). After stirring under a hydrogen atmosphere for 2 h, the mixture was filtered through Celite. The filtrate was concentrated to yield the title compound as a white solid (0.098 g, 91%): 1H NMR:

Workup

  1. filtrationthe mixture was filtered through Celite
  2. concentrationThe filtrate was concentrated

Sources & evidence

ORD record
ord-88634d6f622e4aaf9fb702900d54b55f
Source dataset
uspto-grants-2003_02
Patent number
US06518267B1

Reaction notes

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