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HRID1059253

反应详情

EQUATION

反应方程式

HRID 1059253 的结构方程式

REACTANTS

反应物

3
结构：O=C([O-])[O-].[Na+].[Na+]
HCID10340

Carbonic acid sodium salt (1:2)

CNa2O3

结构：COc1ccccc1Br
HCID11358

Benzene, 1-bromo-2-methoxy-

C7H7BrO

结构：OB(O)c1ccc(F)cc1
HCID285645

4-Fluorophenylboronic acid

C6H6BFO2

PRODUCTS

生成物

1
结构：COc1ccccc1-c1ccc(F)cc1
HCID13089541

4'-Fluoro-2-methoxy-1,1'-biphenyl

C13H11FO

收率 84.5%

AUXILIARIES

试剂、催化剂与溶剂

1
结构：c1ccc([P](c2ccccc2)(c2ccccc2)[Pd]([P](c2ccccc2)(c2ccccc2)c2ccccc2)([P](c2ccccc2)(c2ccccc2)c2ccccc2)[P](c2ccccc2)(c2ccccc2)c2ccccc2)cc1
催化剂HCID178418397

未命名化合物

PROCEDURE

实验过程

By the reaction in the same manner as in Example 4-(ii) using 2-bromoanisole (8.91 g), 4-fluorophenylboronic acid (10.0 g), 2M aqueous sodium carbonate solution (47.6 ml) and tetrakis(triphenylphosphine)palladium(0) (2.20 g), the title compound (8.14 g) was obtained as colorless needle crystals.

WORKUP

后处理

  1. customBy the reaction in the same manner as in Example