Sodium Bicarbonate → HCID 21905845, compound

HRID 1059393Notes

Reaction equation

HRID 1059393 reaction equation
C(O[CH:4]=[CH:5][C:6]1[N:14]=[CH:13][N:12]=[C:11]2[C:7]=1[NH:8][CH:9]=[N:10]2)C.C(=O)(O)[O-:16].[Na+]>Cl>[N:14]1[C:6]([C:5](=[O:16])[CH3:4])=[C:7]2[C:11]([N:10]=[CH:9][NH:8]2)=[N:12][CH:13]=1

Participants

4

Reactant 2

HCID 516892Sodium BicarbonateHCID 57291634HCID 57291634, compound

Product 1

HCID 21905845HCID 21905845, compound

Reagents, catalysts & solvents 1

HCID 313Hydrochloric AcidSolvent

Procedure

1.04 g of 6-(ethoxyvinyl)purine was dissolved in 80 ml of 1 N hydrochloric acid and stirred at room temperature for 15 hours. After neutralizing with a saturated aqueous solution of sodium bicarbonate, it was extracted with dichloromethane and the organic layer was dried over anhydrous sodium sulfate. After distilling off the solvent under reduced pressure, 0.70 g of crude title compound was obtained as a colorless oily substance.

Workup

  1. extractionwas extracted with dichloromethane
  2. dry with materialthe organic layer was dried over anhydrous sodium sulfate
  3. distillationAfter distilling off the solvent under reduced pressure

Sources & evidence

ORD record
ord-65aa339e9ba8411b8f6b54b7184d29a0
Source dataset
uspto-grants-2003_02
Patent number
US06518423B1

Reaction notes

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