Diethyl Ether → HCID 10997378, compound

HRID 1060369Notes

Reaction equation

HRID 1060369 reaction equation
ClC1C=C(C=CC=1)C(OO)=[O:6].[C:12]1([O:18][CH2:19][C:20](=[CH2:22])[CH3:21])[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.CCOCC.C(=O)(O)[O-].[Na+]>C(Cl)(Cl)Cl>[O:6]1[C:20]([CH3:21])([CH2:19][O:18][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)[CH2:22]1

Participants

6

Reactant 4

HCID 3283Diethyl EtherHCID 70297m-Chloroperbenzoic acidHCID 79893(2-Methylallyloxy)benzeneHCID 516892Sodium Bicarbonate

Product 1

HCID 10997378HCID 10997378, compoundYield 83%

Reagents, catalysts & solvents 1

HCID 6212ChloroformSolvent

Procedure

To a solution of 3-chloroperoxybenzoic acid (70% pure, 4.2 g, 17 mmol) in 40 mL of chloroform was added methallyl phenyl ether (2.5 g, 16.87 mmol). The mixture was stirred at room temperature for 5 hours then worked up by pouring into ether and sodium bicarbonate. The organic phase was washed with sodium bisulfite, sodium bicarbonate, and sodium chloride, dried over anhydrous sodium sulfate and evaporated to give 2.3 g of 1,2-epoxy-2-methyl-3-phenoxypropane.

Workup

  1. washThe organic phase was washed with sodium bisulfite, sodium bicarbonate, and sodium chloride
  2. dry with materialdried over anhydrous sodium sulfate
  3. customevaporated

Sources & evidence

ORD record
ord-355c2d3c3ec04b17911687b1c9d80dcd
Source dataset
uspto-grants-2003_02
Patent number
US06521667B1

Reaction notes

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