Dimethylformamide → tert-butyl N-[4-[3-[5-chloro-3-(3-methoxypropyl)imidazo[4,5-b]pyridin-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

HRID 106110Notes

Reaction equation

HRID 106110 reaction equation
[C:22]([CH3:23])([CH3:24])([CH3:25])[O:26][C:27](=[O:28])[NH:29][CH:30]([CH2:31][C:32](=[O:33])[OH:34])[CH2:35][c:36]1[cH:37][c:38]2[cH:39][cH:40][cH:41][cH:42][c:43]2[cH:44][cH:45]1.[CH3:46][N:47]1[CH2:48][CH2:49][O:50][CH2:51][CH2:52]1.[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([CH2:17][CH2:18][CH2:19][O:20][CH3:21])[c:9]([CH:11]1[CH2:12][NH:13][CH2:14][CH2:15][CH2:16]1)[n:10]2.[O:77]=[CH:78][N:79]([CH3:80])[CH3:81].[P-:53]([F:54])([F:55])([F:56])([F:57])([F:58])[F:59].[n:60]1([O:61][C:62]([N:63]([CH3:64])[CH3:65])=[N+:66]([CH3:67])[CH3:68])[c:69]2[n:70][cH:71][cH:72][cH:73][c:74]2[n:75][n:76]1>>[Cl:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([n:7]1)[n:8]([CH2:17][CH2:18][CH2:19][O:20][CH3:21])[c:9]([CH:11]1[CH2:12][N:13]([C:32]([CH2:31][CH:30]([NH:29][C:27]([O:26][C:22]([CH3:23])([CH3:24])[CH3:25])=[O:28])[CH2:35][c:36]3[cH:37][c:38]4[cH:39][cH:40][cH:41][cH:42][c:43]4[cH:44][cH:45]3)=[O:33])[CH2:14][CH2:15][CH2:16]1)[n:10]2

Participants

7

Reactant 6

HCID 6228DimethylformamideHCID 79724-MethylmorpholineHCID 9886HexafluorophosphateHCID 4641409(Dimethylamino)-N,N-dimethyl(3H-(1,2,3)triazolo(4,5-b)pyridin-3-yloxy)methaniminiumHCID 533979213-(Boc-amino)-4-(2-naphthyl)butyric AcidHCID 867615305-chloro-3-(3-methoxypropyl)-2-(piperidin-3-yl)-3H-imidazo[4,5-b]pyridine

Product 1

HCID 123204779tert-butyl N-[4-[3-[5-chloro-3-(3-methoxypropyl)imidazo[4,5-b]pyridin-2-yl]piperidin-1-yl]-1-naphthalen-2-yl-4-oxobutan-2-yl]carbamate

Sources & evidence

ORD record
ord-eee751feb5604a26a9c4ac422b8bda2c
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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