Dimethyl Sulfide → 1,1-Dimethylethyl 4-(4-fluorophenyl)-3-(hydroxymethyl)-1-piperidinecarboxylate

HRID 106144Notes

Reaction equation

HRID 106144 reaction equation
[BH3:27].[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([C:21](=[O:22])[OH:23])[CH:11]([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1.[CH2:28]1[O:29][CH2:30][CH2:31][CH2:32]1.[CH3:24][S:25][CH3:26]>>[C:1]([CH3:2])([CH3:3])([CH3:4])[O:5][C:6](=[O:7])[N:8]1[CH2:9][CH:10]([CH2:21][OH:22])[CH:11]([c:14]2[cH:15][cH:16][c:17]([F:20])[cH:18][cH:19]2)[CH2:12][CH2:13]1

Participants

5

Reactant 4

HCID 1068Dimethyl SulfideHCID 6331BoraneHCID 8028TetrahydrofuranHCID 22228421HCID 22228421, compound

Product 1

HCID 226439871,1-Dimethylethyl 4-(4-fluorophenyl)-3-(hydroxymethyl)-1-piperidinecarboxylate

Sources & evidence

ORD record
ord-fbe2f35d15e94806a9224038e3a7aaa0
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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